Ready to quit smoking?


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Researchers are studying a novel approach to smoking cessation that involves the use of a psychedelic in a safe and supportive setting


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Johns Hopkins University School of Medicine is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The study involves free cognitive behavioral therapy and treatment provided in a comfortable and supportive setting. Transdermal nicotine patches, an FDA-approved smoking cessation treatment, may be provided in this study.

The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions. Questionnaires, interviews, MRI scans, and biological measures of smoking will be used to assess the treatment's effect on mood and smoking.


Volunteers must be daily smokers who are currently seeking to quit smoking permanently. They must between the ages of 21 and 65, and must live within traveling distance of the Johns Hopkins Bayview campus in Baltimore, MD.

Volunteers will receive no monetary compensation.

If you would like to discuss the possibility of volunteering please call 410-550-1972.

Principal Investigator: Matthew W. Johnson, Ph.D.

Protocol: NA_00016166